The vaccine proved safe Mesothelioma

According to a study recently conducted by a cancer research laboratory in the Netherlands, the newest of new vaccines to prevent and treat mesothelioma mesothelioma, a form of cancer that comes from exposure to asbestos. The researchers have tested the vaccine on 10 patients who had been diagnosed with mesothelioma, with all of them showed increased levels of antibodies against the disease and three of them showed that the tumor has decreased in size.
The study, published in American Journal of Respiratory and Critical Care Medicine, explains how vaccines work by creating dendritic cells antigen in malignant mesothelioma tumors in the lining fluid in the lungs of the patient. Dr Joachim Aerts, also the author of the study and lung specialist at the Erasmus Medical Center in Rotterdam, said that the approach using the patient's immune system to attack tumors and is useful for creating immunity to the disease, compared with conventional radiation or chemotherapy treatments.

Dr. Aerts said that this is one of a relatively new form of treatment called immunotherapy for cancer. Mesothelioma vaccine can be used and relatively safe, with minimal side effects when compared with current treatment methods. He expressed the hope that further study could improve the survival rates of patients with diseases mesotelioma. Currently, patients diagnosed with mesothelioma, the prognosis of his life just to stay less than two years.

Patients who had been exposed to asbestos typically do not show symptoms of mesothelioma for several years or even decades, after the initial exposure period. At that time, mesothelioma will continue to run metastases in the lung, and seep into other organs. Another aspect of this study is that the vaccine could be a direct treatment for workers exposed to asbestos.

Although the side effects shown by the patients in this study was not as bad as experienced by patients undergoing chemotherapy or radiation treatments, one of the potential effects derived from changes of the immune system of patients during immunotherapy. The study noted that patients recover quickly and shows no signs of autoimmune disease related.

Dr. Aerts notes that there is potential for problems exist on immunosuppressive disorders. He said that the main problem for the treatment of mesothelioma is a tumor to create an environment in pleural mesothelium which can reduce the effects of the vaccine. He mentioned that the next step in vaccine development is how to provide immunosuppressive around to improve the effectiveness of cancer treatment.

Dr. Aerts and her fellow researchers have done some tests on the effects on dendritic cells and how they may affect cancer tumors in mice. Previous studies have shown that vaccination produces antibodies needed to destroy malignant cells and keep the healthy tissue around it to produce specific immunity.